Well, yes, I think it does. I am currently writing a prequel to the Georgia Pattison series. It is called "Whistles After Dark". All the GP mysteries have musical titles and this one is from Rudyard Kipling's poem "Smugglers' Song".
The story is set in Whitby, a place I thought I knew well until I visited last week and discovered that, not only would my tunnel/cave angle not work, I would also have to put the body on the wrong beach. If my reader wants to tread in Georgia's footsteps, it isn't going to help if said reader can't find his/her way around. And so, major rethink. And that is the problem. At the same time, I know too much and too little about my setting.
Do I need to start again or can I re-jig the story to fit the setting? Whichever way the decision goes, I am going to be forced to do more research and that, in itself is a problem and I believe, a damper on my creativity. Which is why I am sitting here playing with maps and diagrams and pretending it isn't displacement activity.
Perhaps I would do better to heed the late Brian Clemens's mantra. "Arse on seat. Pen on paper" and see what happens. Isn't that why we play with 'what-if?'